Built on studies.
Not hype.

Every active is disclosed with its exact dose. Explore the human evidence behind the ingredients, how closely each study matches Ava, and where the science is still developing.

Abstract black and white cellular texture Evidence, read in context.
16Disclosed active nutrients
3Functional systems
0Proprietary blends
3rdParty tested

Context changes
the conclusion.

“Science-backed” means little without the study design, population, ingredient form and dose. We show the match as well as the limitations.

01

Human evidence first

Randomised human trials carry more weight than mechanisms or laboratory findings alone.

02

Dose and form matter

We compare the researched amount and extract specification with the amount and form in Ava.

03

Limitations stay visible

Mixed findings, small samples and different populations are shown—not edited out.

Sustained support,
without the spike.

Ava designTypical stimulant profile

Illustrative model only. This graph explains the formulation strategy; it is not measured clinical outcome data for the finished Ava product and does not predict an individual response.

Find the
evidence.

Search selected human trials and evidence reviews relevant to Ava’s ingredients. Filter by ingredient or by the role it plays in the formula.

Ingredient
Function
10 studies shownExternal links open PubMed ↗
CiticolineRCT · 2021

Citicoline and memory in healthy older adults

100 participants · 500 mg/day · 12 weeks

Relevant dose; population had age-associated memory impairment.Read study ↗
Nicotinamide ribosideRCT · 2019

Safety and NAD+ metabolism

140 participants · 100–1,000 mg/day · 8 weeks

Shows a biomarker effect; does not establish a subjective energy benefit.Read study ↗
Lion’s maneRCT · 2009

Lion’s mane in mild cognitive impairment

30 participants · 3 g/day powder · 16 weeks

Promising outcome; form, dose and population differ from Ava.Read study ↗
Coenzyme Q10Crossover RCT · 2008

CoQ10 during a fatigue-inducing physical task

17 participants · 100 or 300 mg/day · 8 days

Small sample; strongest signal appeared at the higher dose.Read study ↗
Acetyl-L-carnitineEvidence review · 2017

ALCAR for cognitive enhancement

Cochrane evidence review

Too little reliable evidence for conclusions in healthy adults.Read review ↗
N-Acetyl-L-CysteineSystematic review · 2017

NAC and human cognition

Review of clinical evidence

The literature was heterogeneous and underpowered for firm conclusions.Read review ↗
AstaxanthinRCT · 2010

Astaxanthin and oxidative biomarkers

0, 2 or 8 mg/day · 8 weeks

Dose-aligned biomarker research; not a direct performance outcome.Read study ↗
AstaxanthinMeta-analysis · 2024

Fatigue, motor function and cognition

11 RCTs · 346 healthy participants

Cognitive accuracy was marginal; reaction time was not significant.Read analysis ↗
Rhodiola roseaRCT · 2014

Rhodiola for shift-work fatigue

48 nursing students · 364–728 mg/day · 42 days

The primary result favoured placebo—an important contradictory finding.Read study ↗
Panax ginsengCrossover trial · 2020

Ginseng, attention and perceived stress

Pilot human crossover research

Results are extract-specific and cannot be transferred automatically.Read study ↗

Transparency before certainty.

The research above evaluates individual ingredients, often in different populations, forms, doses and durations. It does not prove that the finished Ava formula will produce identical outcomes.

Ava is a food supplement, not a medicine, and is not intended to diagnose, treat, cure or prevent disease.

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